Varicella zoster virus immunity in dermatological patients on systemic immunosuppressant treatment

Abstract

Background:  Primary varicella infection is caused by varicella zoster virus (VZV), a herpesviridiae. It is a common childhood infection, which is usually benign but can occasionally cause morbidity and mortality. In immunosuppressed adults, atypical presentation and disseminated disease can occur with significant morbidity and mortality. A VZV vaccine is available.


Objectives:  This study was designed to measure the prevalence of immunity to VZV and to determine the predictive value of a self-reported history of varicella infection in a population of dermatological patients receiving systemic immunosuppressant therapy. We sought to assess the ...

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